Biomarker discovery by counting extracellular vesicles
Extracellular vesicle detection in body fluids
- ISO-certified
- Reproducible
- Publication-ready reporting
Unlocking the Secrets of Extracellular Vesicles
Extracellular vesicles (EVs) are membrane-enclosed particles naturally released by cells in the body. EVs are thousands of times smaller than a cell and they are present in body fluids such as blood, cerebrospinal fluid, saliva, and urine. Analysis of EVs provides minimally invasive and novel biomarkers from easy accessible body fluids or “liquid biopsies”
Overcoming the Detection Barrier
Extracellular vesicles (EVs) are subcellular in size and therefore are too small to be detected with routine laboratory instruments. In blood, EVs are vastly outnumbered by lipoproteins, further complicating their characterization. For EVs to become reliable cardiovascular biomarkers, their identification and quantification require robust standardization, calibration, and clinical validation
How EVcount works
Precision at the Speed of Science
Our platform enables multi-label phenotyping of EVs using advanced flow cytometry
Speed:
Quantification in under 2 minutes per sample, processing up to 30,000 particles per second
Precision:
High-sensitivity detection of EVs with diameters down to 90 nm and precise size determination
Quality:
ISO 15189-certified analytics providing MIFlowCyt-EV-compliant reports for faster publication
Sensitivity:
Tekst: Quantifies concentrations as low as 10⁵ EVs/mL with sensitivities equivalent to 10 fluorescent molecules.
Why Choose Us
Ready to advance your research?
EVcount combines decades of pioneering expertise with continuous innovation in R&D. Since 1997, our founders have been at the forefront of single-EV characterization, supported by state-of-the-art infrastructure and a unique depth of expertise. Our ISO 15189-certified workflows ensure reproducible, high-quality EV data you can trust. We further provide a 10% discount to academic customers.
Next-Generation Cardiovascular Liquid Biopsy
EVs are rapidly emerging as one of the most promising frontiers in cardiovascular research. Continuously released into the bloodstream by all cell types, they provide real-time insight into endothelial dysfunction, myocardial injury, thrombogenicity, and vascular inflammation
Track record & Expertise
Pioneering the Field Since 1997
Lead authors of the MIFlowCyt-EV reporting framework
Discovered swarm detection in microparticles
First to quantify EV refractive index by flow cytometry
Pioneered absolute EV size determination
Identified the dilution paradox
